How is Kalman syndrome diagnosed, or delayed puberty
Kalman syndrome (KS) is a rare genetic disease in humans. It is determined by the delay, the absence of signs of puberty in combination with the absence or violation of…

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Kalman syndrome.

How is Kalman syndrome diagnosed, or delayed puberty

Kalman syndrome (KS) is a rare genetic disease in humans. It is determined by the delay, the absence of signs of puberty in combination with the absence or violation of the sense of smell.
Diagnosis of the syndrome is often difficult, since up to adolescence in a child, symptoms may be unexpressed or absent altogether. The absence of pubertal changes that are detected by visual examination is important in diagnosing the patient’s condition. In addition, other diagnostic tests are performed to detect, first of all, decreased smell, genetic mutations or structural disorders of the endocrine glands that can cause similar symptoms.
Disease history

The most distinctive feature that usually prompts patients to seek medical attention is a partial or complete absence of puberty. Men may report symptoms such as decreased libido, erectile dysfunction, decreased muscle mass, and decreased aggressiveness. Continue reading

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